Obesity can be defined as a body mass index ( expressed as weight in kilograms divided by the square of height in meters) that exceeds 30.
There is a strong genetic component to obesity , but environment factors , presumably related to activity and nutrition play a role as well.
Obesity presents a wide range of metabolic and physiologic consequence to those ot affects , and these include frequent occurence of oligo- amenorrhoea
-anovulation / oligo-ovulation.
Infertility and an increased propensity for endometrial hyperplasia and endometrial malignancy are direct result.
The negative effect of obesity upon fertility was described by Hippocrates, who wrote in his Essay on the Scythians
‘People of such constitution cannot be prolific …fatness and flabbiness are to blame.
The womb is unable to receive the semen and they menstruate infrequently and little’ (Lloyd et al. 1978).
Obesity can exert effects upon the hypothalamic–pituitary–ovarian (HPO) axis and as such disturb menstrual cyclicity and ovulation.
Obese women are more likely to experience pregnancy loss once pregnant, and elevated miscarriage rates are seen following natural conception, ovulation induction and assisted conception.
Adipose tissue has been shown to disturb sex hormone secretion and bio availability. Indirectly, obesity exerts its effect via leptin, insulin and the adipokines.
Amrutwel Women’s Clinic
Kharghar , Navi Mumbai
Ex Professor and HOD D Y Patil college Nerul