Salient features of shvaasa roga & Hridroga ;
Rajasa is told as first hetu in shvaasa roga , as per acharya chakrapani , Rajasa is in vaata prakopaka gana . pollen grains/ allergens react with Mast cells, dendritic cells and in turn activates TH2 cells & eosinophil , neutrophil (inflammatory cells ). There is secretion of inflammatory mediators (histamines, leukotriens, PAF , etc ) , which lead to bronchospasm, plasma exudation, mucus secretion , etc due to underlying inflammation.. Asthma may be regarded as a disease with continuous inflammation and repair proceeding simultaneously..Please note one thing that without pitta there may be inflammation. Best example ; in abhighaataja jvara , vaata prakopaka and rakta dushti are present which manifest jvara , shotha , vaivarnya and vedanaa , similar to features of inflammation.So , if allergens are triggering factors , they will work as vaata prakopaka hetu and in turn develop inflammatory response , hypersensitivity of bronchial smooth muscles and manifest dyspnea , wheezing cough , as sine qua nan of bronchial asthma.. Histamines and related factors are synthesised and secreted by interplay between triggering and genetic factors.. And there is too many triggering factors , can be classified as vaata , pitta and kapha prakopaka .Earlier , researchers found the role of vasoactive intestinal peptides as an intrinsic factors to play role in pathogenesis of bronchial asthma. Histamines and its receptors are major inflammatory agents, H1, H2, H3 histamines receptors are isolated.. H2 receptors are found as gastric acid stimulants.. Aamaashaya is told origin of shvaasa roga , considering stomach and upper intestine , the correlation looks logic.. After virechan these peptides may be excreted out , further research is needful to reach on any accepted hypothesis…
As per Dutch hypothesis , bronchial asthma , chronic bronchitis , and emphysema are variations of the same basic disease , I found the same approach while studying charakokta shvaasa roga.. Shvaasa roga -praanavasa sroto dushti – hridaya dushti – rasavaha srotodushti..-rasaadi dhaatunaam upashoshana (aruchi , paandu , kaamala , shothaadi ) . COPD -Pulmonary hypertension -cor pulmonale -systemic venous congestion -raised jvp , congestive hepatomegaly ( jaundice, indigestion, ascites etc), edema.. Marma upaghaata – hridaya upaghaata – shotha.. Acharya chakrapani ; marmopaghaata iha doshakrita Eva geyah..
Gadaatichaara ( iti rogaanaam asamyaka upachaara ; shvaasa rogasya asamyaka upachaara ) – hridroga.. (Ch.chi.26). Vaivarnya in hridroga can be seen as cyanosis, pallor , icterus , splinter haemorhage , etc. Moorchchha in hridroga due to Aortic stenosis , obstructive cardiomyopathy , hypertension , acute coronary syndrome , arrhythmia , thromboembolism ,etc..
.Prof. Dr. Satyendra Narayan Ojha ,
MD (KC), Ph.D.
Director , Yashawant ayurveda college , Post graduate teaching and research center ,
Kodoli ,Panhala , Kolhapur..